R&D : Versatile Contained Filter Drying

Liverpool, England -The PSL small scale contained filter dryer provides maximum efficiency and versatility in R&D kilo labs. This lab scale system has a 0.05 m2 filtration area with 15L liquid capacity and typical 2 to 8L wet cake capacity – perfect for multi product kilo facilities. Typical batch sizes of 1 to 5KG quantities with a compact system that can be easily moved round and receive slurry liquid from multiple reactors.

When developing compounds, containment requirements are always stringent, especially for NCEs (new chemical entities). Containment is achieved via a top mounted PSL ChargePoint, 100mm split valve, for vessel charging. A tilting mechanism, which is integrated into the frame, allows complete inversion of the vessel for contained powder discharge via the same spilt valve. The PSL ChargePoint achieves < 10 microgrammes/m3 containment, further ancillaries can be added to the standard valve to achieve < 1 microgramme/m3.

This small mobile filter dryer is ideal for API chemical kilo labs requiring a solution for filtration and drying of slurry from multiple reactors of various sizes, as is typical in R&D facilities. Compact design enables the unit to be easily moved by a single person, within standard walkway widths, to ensure this filter dryer can be easily moved between labs / rooms.

For added flexibility the base can be fitted with either filter cloth or sintered metallic mesh providing the flexibility required in a busy multi product kilo lab. Again, to maximise versatility, this filter dryer is designed with C22 alloy product contacts for flexibility primarily in solvent usage, the ChargePoint can also be in C22 alloy. 316L vessel and split valve options are available when solvents to be used are known to be less aggressive.

To ensure minimum slurry losses it is important to keep pipe lengths between reactor discharge and filter dryer to a minimum. This small scale unit has been designed with minimal height, enabling use in the tightest of areas.

This complete system, vessel and split valve, is pressure rated to 6 BarG. The vessel has integral spray balls for cleaning in place and a sight glass & light fitted to enable viewing of the process without breaching containment.

This kilo lab filter dryer has an ATEX approved control panel mounted on the trolley, plugs and sockets allow easy connection and disconnection for quick and simple set up in different locations.

This small scale contained filter dryer is simple to set up and operate, its versatility provides an invaluable addition to any kilo lab.

SOURCE: The PSL small scale