Featured Articles
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Biological Treatment Of Ammonia In Wastewaters
By Dr. Rakesh Govind, PRD Tech, Inc.
As human population continues to increase, viability of our natural fresh water resources continues to be threatened due to human activities, especially due to changes in the global nitrogen cycle. Use of fossil fuels for energy production, application of nitrogen-based fertilizers, and release of nitrogen compounds in treated sewage water is causing dramatic increases in bio-available nitrogen.
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Analysis Of Potential Genotoxic Acrylamine And Aminopyridine Impurities In Active Pharmaceutical Ingredients
By Gerd Vanhoenacker, Frank David, and Pat Sandra, Research Institute for Chromatography, Belgium
This application note illustrates the possibilities of the Agilent 1290 Infinity LC system and the Agilent 6460A Triple Quadrupole Mass Spectrometer for quantitative analysis of potential genotoxic impurities (PGIs) in active pharmaceutical ingredients (APIs). A generic approach was used to determine arylamine and aminopyridine PGIs in selected APIs. The influence of column length and mobile phase composition on the recovery of these impurities in real samples were investigated.
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